Dr. Karikó is a biochemist who developed many of the key advances behind mRNA vaccines, which were key to bringing an end to the COVID-19 pandemic and saving countless lives. She was convinced of her approach and kept up her research in the face of numerous setbacks, grant rejections, and even demotion by her university. Her story serves as an inspiration in illustrating the power of scientific conviction and perseverance, in a scientific system where these traits are not always valued.